METiS TechBio Grants Global License for AI Designed T Cell Engager to Boulevard Bio

Jul 6, 2026
METiS TechBio has entered a global licensing agreement with Boulevard Bio, granting exclusive rights to develop, manufacture, and commercialize MTS-128, an AI designed trispecific T cell engager. The deal includes $20 million upfront and up to $1.6 billion in potential milestone payments.

METiS TechBio has entered an exclusive global licensing agreement with Boulevard Bio, granting Boulevard worldwide rights to develop, manufacture, and commercialize MTS-128, a trispecific T cell engager program. The arrangement was announced in a press release.

Under the terms of the agreement, METiS TechBio will receive a 20 million dollar upfront payment and may earn up to 1.6 billion dollars in development, regulatory, and commercial milestone payments. The company will also receive tiered royalties on sales of any resulting products.

MTS-128 was created using METiS TechBio's NanoForge platform, which integrates protein design, drug delivery system engineering, and therapeutic optimization through artificial intelligence. The program is intended to improve target cell killing efficiency and reduce off-target toxicity compared with conventional bispecific T cell engagers.

Founded by a team of MIT-trained scientists, METiS TechBio focuses on AI enabled drug delivery technologies, while Boulevard Bio is supported by Deerfield Management, a healthcare investment firm. METiS noted that the agreement reflects its transition from technology validation toward global commercialization of AI based therapeutic assets.

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