Wolters Kluwer to buy AI clinical decision support company AgileMD for up to $100 million

Nov 14, 2026
Wolters Kluwer Health will pay $40 million upfront, with the rest tied to performance targets, and plans to combine AgileMD with UpToDate.

Wolters Kluwer Health has signed an agreement to acquire AgileMD for up to $100 million, the company said in a release. Of that, $40 million is paid upfront and the balance is deferred and contingent on reaching certain performance targets.

San Francisco-based AgileMD, founded in 2011, provides AI-powered clinical decision support. Its Pathways product brings local guidelines into the electronic health record workflow, and its eCART system is a real-time AI clinical surveillance engine. The company expects to reach $7 million in annual recurring revenue by the end of 2026, and all 23 employees will join Wolters Kluwer Health, according to the release.

"Combined with UpToDate Expert AI and our partnerships, AgileMD will serve as a vital enabler for true UpToDate ubiquity in healthcare," said Yaw Fellin, senior vice president of Wolters Kluwer Clinical Solutions. Wolters Kluwer says UpToDate Expert AI has been adopted by more than 2,700 US hospitals and health systems since its introduction in September 2025.

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