RNA Horizons 2025 Showcases Advances in RNA Therapeutics in Palermo

The RNA Horizons Therapeutics Symposium 2025 brought together scientists, clinicians, and biotech innovators in Palermo, Italy, to present new findings in RNA biology and medicine, announced in a press release. The three-day event followed the 2024 edition in Porto and focused on RNA’s growing role in treating oncology, metabolic, and neurodegenerative diseases.

Key discussions centered on improving RNA delivery and stability, including antisense oligonucleotides and self-amplifying RNA. Highlights featured Prof. Ernesto Guccione’s NATURA assay for high-throughput RNA delivery measurement, Prof. Shai Rosenberg’s transcriptomic modeling for precision therapies, and Prof. Ron Weiss’s miRNA-based logic circuits for selective cancer targeting.

Other presentations included 3D-bioprinted tumoroid models by Prof. Ronit Satchi-Fainaro, studies on splicing dysregulation by Prof. Claudio Sette, and m⁶A-dependent RNA regulation findings from Prof. Rotem Karni. Additional talks expanded the focus to metabolic and neurodevelopmental disorders.

The symposium, organized by RNA Horizons under the CANCERNA consortium, emphasized collaboration across academia, industry, and clinical research. The next RNA Horizons Therapeutics Symposium will be held in Munich, Germany, in September 2026.