OpenAI's GPT-5 and Microsoft AI Lead in Biology Innovations

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Welcome to this week's edition of Life AI Weekly, where we delve into the latest advancements in AI within the healthcare and life sciences sectors. This week, we explore a variety of groundbreaking developments, including AllOne Health's strategic acquisition of three Employee Assistance Programs to enhance AI-driven mental health services. Meanwhile, UbiSim has introduced an innovative AI tool designed to improve nursing education by efficiently analyzing narrative data, thereby better preparing students for clinical scenarios.

In other news, OpenAI's GPT-5 has made strides in wet lab biology, collaborating with Red Queen Bio to improve cloning efficiency through AI-suggested experimental methods. Additionally, the Icahn School of Medicine at Mount Sinai has developed an AI tool to identify harmful genetic mutations, potentially predicting associated diseases. These stories, along with many others, highlight the transformative impact of AI technologies in advancing healthcare and life sciences.

AllOne Health Acquires Three EAPs to Boost AI Mental Health Services

AllOne Health has acquired Carebridge EAP, Comp EAP, and ERC EAP to expand its AI-driven mental health services and national presence. Read more

UbiSim Introduces AI Tool for Nursing Education

UbiSim has launched AI Narrative Analysis to assist nursing educators by transforming simulation data into actionable insights, enhancing learner readiness and saving time on data review. Read more

OpenAI's GPT-5 Advances Wet Lab Biology with Red Queen Bio

OpenAI's GPT-5 has made significant progress in wet lab biology by suggesting new experimental methods that were confirmed through laboratory testing. In partnership with Red Queen Bio, GPT-5 improved cloning efficiency by 79 times through a novel enzymatic mechanism and optimized conditions, highlighting AI's potential in biological research with human oversight. Read more

Mount Sinai Develops AI Tool for Genetic Mutations

Researchers at the Icahn School of Medicine at Mount Sinai have developed an AI tool named Variant to Phenotype (V2P) to identify harmful genetic mutations and predict associated diseases. Read more

FDA Evaluates AI Mental Health Device Regulations

The FDA's Digital Health Advisory Committee convened to discuss regulatory strategies for generative AI mental health devices, focusing on a risk-based approach to ensure safety and effectiveness. Read more

Ultromics Receives Investment from American Heart Association

Ultromics, an AI-driven cardiology solutions company, has secured a strategic investment from the American Heart Association's Go Red for Women Venture Fund. This funding will support the enhancement of early detection of heart failure with preserved ejection fraction (HFpEF) using Ultromics' AI technology, EchoGo. Read more

Bioptimus Launches M-Optimus for Biological Simulation

Bioptimus has introduced M-Optimus, a new model designed to simulate human biology by integrating various biological modalities. This model is expected to aid in drug discovery, clinical trials, and patient care. Read more

Huxley Medical's SANSA Gets FDA Clearance for Home Sleep Testing

Huxley Medical has received FDA clearance for its SANSA device, marking it as the first to diagnose cardiac arrhythmias during home sleep testing. The device combines ECG monitoring with sleep apnea testing, improving patient care by detecting cardiac issues. Read more

Catharina Hospital and TU/e Receive €1.3M for AI Pancreatic Cancer Research

Catharina Hospital and Eindhoven University of Technology (TU/e) have secured €1.3 million from KWF Dutch Cancer Society to enhance early detection of pancreatic cancer using AI. Read more

EU Proposes Simplified AI Regulations for Medical Devices

The European Commission has proposed revisions to streamline regulations for medical devices with AI components, aiming to reduce administrative burdens and improve regulatory coordination. Read more

HHS Seeks Public Input on AI in Clinical Care

The U.S. Department of Health and Human Services has issued a Request for Information to gather public input on accelerating AI adoption in clinical care, with a focus on regulations, reimbursement, and research. Read more

Protego Health Partners with Ogden Clinic for AI Solutions

On December 17, 2025, Protego Health announced a strategic partnership with Ogden Clinic to implement AI-powered solutions aimed at improving revenue cycle operations by preventing denied medical insurance claims and streamlining the appeals process. Read more

AstraZeneca Uses AI in Clinical Trials in Thailand

AstraZeneca is utilizing AI technology in clinical trials across Thailand, achieving a 54.1% positive predictive value with its AI chest X-ray tool. The company aims to enhance patient outcomes and deliver 20 new medicines by 2030. Read more

Parkview Health Partners with Notre Dame for AI Startups

Parkview Health is collaborating with the University of Notre Dame and the 1842 Fund to develop AI-driven digital health startups. The initiative aims to address healthcare challenges in rural areas by launching up to two startups by 2026. Read more

Cedars-Sinai and University Health Network Host AI Symposium

Over 200 international leaders in AI, medicine, and surgery gathered at Cedars-Sinai for the second annual symposium, focusing on AI implementation in clinical settings and addressing regulatory and ethical issues. Read more

AI Tool Predicts Nutrition Risks in ICU Patients

Researchers at the Icahn School of Medicine at Mount Sinai have developed an AI tool called NutriSight to predict underfeeding risks in ventilated ICU patients, aiming to improve early nutritional interventions. Read more

No Barrier Secures Funding for AI Medical Translation

Startup No Barrier is using AI to enhance medical translation services, aiming to help over 26 million US residents with limited English proficiency. The company has raised $2.7 million in seed funding and operates in over 100 healthcare sites across 12 states, providing real-time translation in more than 40 languages. Read more

MHRA Seeks Public Input on AI Regulation in UK Healthcare

The MHRA is inviting public contributions to help shape AI regulation in UK healthcare, focusing on patient safety and the future use of AI in the NHS. Read more

FSU Receives $5M Grant for AI Speech Tools

Researchers from Florida State University have been awarded a $5 million grant to develop AI tools to assist children with speech and language challenges. Read more

Corti's GIM Method Tops Hugging Face Benchmark

Corti, a healthcare AI company, has introduced its Gradient Interaction Modification (GIM) method, achieving the top position on the Hugging Face Mechanistic Interpretability Benchmark. This method enhances AI model understanding, crucial for healthcare applications, and is now open source. Read more

PRISM BioLab and Talus Bioscience Partner for AI-Driven Drug Discovery

On December 17, 2025, PRISM BioLab and Talus Bioscience announced a collaboration to discover novel inhibitors targeting transcription factors and protein-protein interactions using AI technology. Read more

Galbot Raises $300 Million, Valued at $3 Billion

Galbot has secured over $300 million in new funding, elevating its valuation to $3 billion. The investment will support technology development and expansion in industries like manufacturing and healthcare. Read more

Microsoft AI Advances in Biology and Medicine

Researchers at Microsoft are working on AI technologies to improve understanding of biological systems, with the goal of transforming healthcare through personalized medicine. Read more

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OpenAI's GPT-5 and Microsoft AI Lead in Biology Innovations - Life AI Weekly #47

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