CorePlus Puerto Rico Validates AI for Cervical Cytology Quality Control

CorePlus Puerto Rico has published a groundbreaking study validating the use of artificial intelligence (AI) and whole slide imaging (WSI) as a 100% quality control tool in cervical cytology workflows, announced in a press release. The study, published in the peer-reviewed journal Cancer Cytopathology, highlights the scientific rigor and clinical relevance of this approach.

The study evaluated the performance of the Techcyte SureView™ system on 1,442 digitized slides from ThinPrep® and SurePath™ cervical cytology samples. The slides were scanned using the 3DHISTECH P1000 DX scanner under both dry and water immersion scanning profiles. A board-certified cytopathologist reviewed AI-identified objects of interest and compared them to results obtained through traditional light microscopy.

The results demonstrated that the SureView™ system using the water immersion profile significantly outperformed both dry scanning and manual microscopy in detecting squamous and glandular abnormalities. Key performance metrics included 97% accuracy, 82% sensitivity, 99% specificity, 98% negative predictive value, and 86% positive predictive value.

Following successful validation, CorePlus has fully integrated the Techcyte SureView™ system as a 100% QC tool in its laboratory operations, marking a major step forward in adopting digital and AI technologies to enhance diagnostic accuracy, laboratory efficiency, and patient care.