AI Oxygen System Improves Target Range Time in Hospital Trial

August 03, 2026
A CU Anschutz led trial found that an automated oxygen delivery system helped hospitalized patients spend more time in their target oxygen range than standard care.

University of Colorado Anschutz announced in a press release that a clinical trial found an automated oxygen delivery system helped hospitalized patients spend more time in their target oxygen range than standard care. The SAVE-O2 AI trial was published in JAMA Internal Medicine and presented at the Military Health System Research Symposium.

The multicenter trial enrolled 300 adults receiving supplemental oxygen at four U.S. hospitals, including UCHealth University of Colorado Hospital. Patients were randomly assigned to standard care managed by clinicians or autonomous oxygen titration using the O2matic PRO100 system.

Patients in the automated group spent 85 percent of their time in the target oxygen range, compared with 63 percent in the standard care group. The study also found reduced exposure to both low and high oxygen levels.

The O2matic PRO100 continuously monitored oxygen levels and adjusted oxygen flow. The research team plans to further evaluate the system in emergency transport and prehospital settings.

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