Caris Life Sciences Raises 2025 Revenue Guidance After Strong Q3 Results

Nov 6, 2025
Caris Life Sciences reported third-quarter 2025 revenue of $216.8 million, up 113% year-over-year, and raised its full-year revenue guidance to $720–$730 million.

Caris Life Sciences reported third-quarter 2025 revenue of $216.8 million, a 113% increase from the same period last year, announced in a press release. The company attributed the growth to strong performance in its molecular profiling services.

Caris completed 50,763 clinical therapy selection cases during the quarter, marking an 18.2% increase year-over-year. Gross margin improved to 68.0%, representing a 2,432 basis point increase from the prior year period.

The company reported a net income of $24.3 million and positive adjusted EBITDA of $51.2 million. Operating activities generated $62.4 million in net cash flow, with free cash flow reaching $55.3 million.

Based on its performance, Caris raised its full-year 2025 revenue guidance to a range of $720 million to $730 million, representing expected growth of 75% to 77% compared to 2024.

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